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You helped develop a revolutionary clot-busting drug for COVID-19.

Up to 75 per cent of critically ill COVID-19 patients in intensive care develop life-threatening blood clots that can trigger stroke or heart attack, or lead to long-term organ damage or even death. Our groundbreaking new clot-busting drug has already proven to be safer and more effective than existing treatments, and is now urgently moving towards global phase 2 trials – testing its effectiveness and safety in critically ill COVID-19 patients. In just months, this drug could be used all over the world to protect patients from deadly blood clots and save lives.

You helped discover why hearts fail.

Over half a million Australians have heart failure, with 61,000 new cases diagnosed each year. In an innovative world-first project examining cryo-preserved human hearts, we have discovered how the heart deals with injury and clotting, and how heart failure differs between men and women. We will further investigate these discoveries in search of new therapies that could treat, or even better, prevent heart failure in people.

You helped trial a new way to detect atrial fibrillation.

People with atrial fibrillation (AF), a common heart rhythm disorder, are five times more likely to have a debilitating stroke. We have successfully trialled an innovative tool to quickly scan and pick up signs of AF in the faces of several people at once. This new technology could ensure early diagnosis and treatment of AF, preventing stroke and protecting people from the life-long disability and brain damage that can result. We continue to lead a global push to improve detection of AF in the community.

I believe the work of the Heart Research Institute will save generations of families.

Larissa
open heart surgery patient

Thank you for over 30 years of discovery.

For over 30 years, we have been working towards a future without cardiovascular disease (CVD), supported by generous donors like you. These are just some of the incredible breakthroughs we have been able to achieve together.

  • 2020 Developed a clot-busting drug that could revolutionise the way blood clots seen in COVID-19, stroke and other diseases are treated
  • 2020 Discovered more about the mechanism of heart failure, paving the way for exciting new therapies
  • 2017 Discovered a molecule that can predict who is most at risk of developing diabetes, 12 years in advance
  • 2013 Uncovered the link between diabetes and CVD, a world-first and a discovery with the potential to save lives
  • 2005 Demonstrated that low-birth weight babies have thicker aortic walls, possibly predisposing them to greater risk of CVD later in life
  • 2003 Investigated the role high-density lipoproteins ‘HDL’ (good cholesterol) plays in the protection against atherosclerosis
  • 1998 Discovered that both protein and fat oxidation can have a major effect on heart disease and enter previously uncharted territory as we try to understand how protein oxidation can actually be prevented
  • 1995 Proved the link between passive smoking and heart disease, research that became pivotal in the global move to ban smoking in public places

Your support is vital.

Cardiovascular disease is responsible for one death every 12 minutes. With your support, we are fighting to change that.

Over 70% of the funding for our life-saving work comes from a community of generous donors like you, and the challenges of the pandemic have highlighted just how important your support is to suffering patients. The only thing that gives us a fighting chance against devastating illnesses like heart disease and the coronavirus is medical research – and people like you.

From the bottom of our hearts, thank you.

Your ongoing support allows us to plan for the future and enables our research to advance to the breakthrough stages that could one day save the life of a loved one... or even your own.

Without the research and the technology that’s available, I definitely wouldn’t be alive today.

John
triple bypass surgery patient and stent recipient

See the impact of your support.

Your support is vital to keeping our scientists in the labs so they can keep fighting to protect the community from heart disease. We would love to welcome you to an in-person or virtual visit of our research facilities in Sydney, where you can meet the scientists you are supporting and see first-hand the impact you have had. Find out more and register your interest here.

You have had a huge impact. Your generosity enables our research today – for the treatments and cures of tomorrow. Thank you.

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HRI breakthrough drug for coronavirus

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